Platelet Spleen Index is a Noninvasive Technique to Detect Esophageal Varices in Cirrhotics

Background: noninvasive esophageal parameters may prevent the need for an esophagogastroduodenoscopy. Liver cirrhosis patients benefit from PC/SD ratio and platelet count to spleen diameter (PC/SD) ratio, both of which are yet useful indicators liver progression. Objective: This study aimed evaluate diagnostic accuracy index diagnosis gastric varices in with cirrhosis, using esophagogastroduodenoscopy as reference standard. Methodology: A-Cross-sectional descriptive validation The was conducted over course three months, October, 2019 December 2019. At Gastroenterology A tertiary care hospital. comprised 90 participants. In addition requisite blood tests, abdominal ultrasonography used size spleen. TYPE SIZE sensitivity is 83%, specificity 66%, 83% Variations were found 24% cirrhotic individuals. Cirrhosis defined accordance operational definition. Patients' samples collected at hospital laboratory a complete count, ultrasound performed Radiology department, upper GI endoscopy endoscopic suite screeningpurposes. Results: With reverence ages study's varied 55.0 89.8. Ninety (44.7%) women, while remaining 48 (55.3%) males. Hepatitis C most common (almost 50%), followed by hepatitis B, cryptogenic Wilson's disease. B accounted cases. (1.2% total). There distinct severity levels varices. 12 (14.2%), 23 (27.7%), 32 (37.7%), 38 varies (21.8%). Out total 90, 69.5% determined be Child's Pugh stage A, 24.9% 4.7% grade C. two-by-two table, we calculated likelihood (sensitivity plus positive negative predictive values) gastro varices, it came out 78%. ROC curve also generated. stratified according their age, gender, cause condition. Practical implications: will provide data health workers use non-invasive technique lower procedure costs associated complications detect Esophageal cirrhotics Conclusion: It possible that amount unnecessary esophagogastroduodenoscopies reduced if method diagnosing gastroesophageal widely used. keywords: varies, Cirrhosis, Platelet index, Non invasive method,